OPERATION CHASTISE: THE RAF’S MOST BRILLIANT ATTACK DURING WORLD WAR II by Max Hastings

Operation Chastise by Robert Taylor (Lancaster)

During World War II a debate raged among allied strategists as to how much civilians should be targeted to defeat the Nazis.  As the Germans wreaked havoc on civilian populations throughout Europe and the United Kingdom the defeat of Hitler’s henchmen was deemed a necessity no matter the cost.  Max Hastings, a British journalist and historian, the author of numerous volumes ranging from World War I, the Battle of Britain, World War II, Winston Churchill and Vietnam tackles the issue of civilian casualties in his latest effort, OPERATION CHASTISE: THE RAF’S MOST BRILLIANT ATTACK DURING WORLD WAR II.

By May 1943 the British had accomplished little against the Nazis when compared to the effort and suffering of the Soviet Union which was finally making its push from Stalingrad westward.  Further, Winston Churchill was under a great deal of pressure to produce victories to stir the English people.  The allied grand strategy to this point was cautious to allow their slow industrial buildup to take hold before making a stronger presence on the battlefield.  To this point their most significant action concerned the use of heavy bombers.  The British decided in October 1940 that instead of pursuing largely vain efforts to locate power plants, factories, and military installations the Royal Air Force (RAF) would bomb German cities which would continue until 1945 and the end of the war.  The C-in-C Bomber Command Chief Marshall Sir Arthur Harris believed that air attacks on Germany could render a land invasion of Europe as unnecessary.  Winston Churchill did not care for Harris, but he believed in his sense of purpose and his ability to create positive publicity, i.e., the thousand bomber raids” over Cologne in May-June 1940.  There were a number of skeptics concerning Harris’ approach to winning the war, but Harris’ publicity machine and ability to put out positive bombing figures made him an important component in RAF leadership.  By “by war’s end, Bomber Command was capable of reigning upon Hitler’s people in a single twenty-four-hour period as many bombs as the Luftwaffe dropped during the course of its entire 1940-41 blitz on Britain.”

Barnes Wallis

(Barnes Wallis)

It is at this point that Hastings introduces his main topic the bombing of German dams as a means of destroying Hitler’s Ruhr Valley industrial complex. The Ruhr and its industries accounted for 25% of Germany’s entire consumption, much of it derived from the Mohne reservoir.  Flooding the low-lying Ruhr Valley would render railways, bridges, pumping stations, and chemical plants inoperative.  The key figures that Hastings explores in depth are Barnes Wallis, an engineer who become the hero of Operation Chastise, the mission to destroy the Mohne Dam as well as others, as he was able to design and develop the immense bomb that could “bounce” along the water to breach the Mohne Dam.  Next, Guy Gibson who led the 617 Squadron of the RAF Bomber Command that would bomb the dams of north western Germany employing a revolutionary new weapon that required plans to fly at an extremely low level after conducting over 170 successful bombing missions over Germany.  Ralph Cochrane, Harris’ subordinate was in charge of the mission who was one of the RAF’s ablest senior officers who has been described as a “ruthless martinet.”  Air Chief Marshall Sir Charles Portal, the head of the RAF believed in assaulting urban areas and was a prime mover behind Operation Chastise.  Arthur Collins, a scientific officer in Harmondsworth’s “Concrete Section” who proved to Wallis that “a relatively small charge might achieve a wholly disproportionate result if it was detonated sub-aqueously and close to the target, using a timer or a hydrostatic pistol: it could thus harness the power of the water mass to channel the force of the blast.”  Lastly, Sir Arthur Harris, the commander, who when pulled over by the military police at one time and was admonished that he could have killed someone, he responded “I kill thousands of people every night.”

Guy Penrose Gibson, VC.jpg

(Guy Gibson)

Hastings does a marvelous job explaining the scientific experimentation, the training of the pilots, the shifting of resources, the strategic planning of the operation, and the different personalities with their own agendas in detail.  By doing so  Hastings highlights his own expertise and command of the material, but also the ability to explain complex information and make it easily understood for the reader.

Hastings introduces numerous pilots, bomb aimers, navigators, wireless operators, and gunners that made up the core of the mission.  These men formed groups of seven for each Lancaster bomber that was sent into Germany the night of May 16, 1943.  Hastings narrative provides intimate portraits of the men and how they interacted and were organized.  The squadron reflected all social classes, but despite a degree of class consciousness they were able to form into workmanlike groups of young men most of whom were in their late teens and early twenties with a sprinkle of men in their thirties.  Among these individuals included are Richard Trevor-Roper, the Squadron Gunnery Leader and bomb aimer who at 27 was the oldest among the squadron; F/.SGT Len Sumpter, a bomb aimer was a shoe makers son who left school at 14; wireless operator Jack Guterman, a very literary young man faced with the decision to follow his pilot Bill Ottley from another command joined the 617th;  F/LT Joseph McCarthy, the only American pilot involved with Operation Chastise who grew up in the Bronx, NY; F/LT John “Hoppy” Hopgood, Gibson’s closest friend; F/LT David Shannon, an Australian pilot; and aircraft navigator Jock Rumbes a pilot washout who became an excellent navigator.  These and many others new by the nature of the mission flying at night at an altitude of under 100 feet over water that their chances of survival were limited and the result is that 52 of the 133 men involved in Operation Chastise would not return.  As Hastings points out, “the margin for error, both for successful attacks and survival was virtually zero.”

Mohne dam before and after 617 squadron's famous Dambuster raid

(Mohne Dam May 16-17, 1943)

 

Hastings provides a blow by blow account of Operation Chastise from its takeoff on May 16, 1943 describing the difficulty of lifting off the ground with such a heavy payload, flying under 500 feet in the air to avoid German radar and flak, the mindset and experiences of the 133 men during the long flight, the final successful delivery of Wallis’ “bouncing bombs,” and the severe losses in planes, five of which crashed before reaching the target area in addition to three more at the site out of nineteen in total that took off on May 16, and the 52 men that perished.  As Hastings correctly concludes, Operation Chastise was a huge extravagance and essentially a gamble, a piece of military theater, rather than serious strategy.  In the end the Mohne and Eder dams were breached causing flood waters that would kill  between 1400-1500 people, half of which were non-German forced laborers.  In addition, the Nazis suffered an undetermined amount of economic and production losses.

Operation Chastise was largely hidden from the public until 1955 when the film, “Dam Busters” was released.  Hastings follows upon the works of other historians like James Holland to describe the events and personalities surrounding the mission whose idea dated back to 1937 and presents it to an audience after conducting voluminous research and interviews over his long career as a war correspondent, journalist and historian.  With the inclusion of maps, charts, and photos Hastings effort has produces a wonderful addition to monographs that focus upon the lesser known operations conducted during World War II, but were extremely important as in this case it reflected the turning of the tide, a small and symbolic step towards the ultimate defeat of Nazi Germany.

OPERATION CHASTISE

Operation Chastise was an attack on German dams carried out on 16–17 May 1943 by Royal Air Force No. 617 Squ

 

VICTIM 2117 by Jussi Adler-Olsen

Berlin street (Imago/Jürgen Ritter)

(Berlin, Germany)

The most despicable tragedy of the last decade has been Bashar al-Assad’s war on the Syrian people to retain power.  The actions of the Russian and Turkish governments have exacerbated the situation that has produced the death of over 400,000 people and created over 5,000,000 refugees.  In VICTIM 2117, Jussi Adler-Olsen’s latest work, the author introduces the Syrian catastrophe at Ayia Naba, a beach in Cyprus as 37 bodies have washed ashore having drowned in the Mediterranean Sea in an attempt to escape their home country.  At the same time there is an emotionally stunted young man who recently graduated high school named Alexander who lives in Copenhagen.  Alexander is a virtual gamer who claims 2080 wins and in his demented mind has added the 37 drowning victims he read about in the newspaper to his total, 2117.  This milestone now reached has set in motion Alexander’s plan to kill his parents and wreak havoc on the public.

 

(Jussi Adler-Olsen, author)

If this plot line was not enough, Adler-Olsen focuses on Joan Aiguader, a self-promoter and a struggling free-lance journalist for a newspaper in Barcelona who has hit rock bottom until he becomes interested in the increasing numbers of refugee drownings, particularly 37 in Cyprus.  Twisting his story line further Adler-Olsen zeroes in Assad, a member of Department Q of the Copenhagen Police  Department who has appeared in most of the author’s previous novels.  It seems that Assad has kept his past hidden from Carl Morck his superior in Department Q who believed that the man who had introduced himself ten years ago as “Hafez el-Assad, a Syrian refugee with green rubber gloves and a bucket by his feet.  But inside he was really Zaid al-Asadi: special forces soldier, language officer, Iraqi, and almost fluent Danish speaker.  The man was one hell of a gifted actor.”   Assad’s tortured past involves what transpired 16 years previously at the hands of a Sunni terrorist and former official under Saddam Hussein named Abdul Azim or Ghaalib, a man who had kidnapped Assad’s pregnant wife and two daughters who Assad believed were dead for all of those years.

For those familiar with Adler-Olsen’s previous novels, VICTIM 2117 will not disappoint.  For those who are reading his work for the first time you probably will become hooked as he has deftly created a story with resonance today as he intertwines a series of plotlines.  Apart from Assad and Morck a number of characters from previous novels appear, though VICTIM 2117 can stand alone.  Adler-Olsen takes the reader back to Fallujah in Iraq at a time when United Nations weapons inspectors are looking for Saddam’s Weapons of mass destruction (WMD).  Events that take place are part of Assad’s past but they tie into a great deal of contemporary evidence, particularly newspaper photos of Marwa, Assad’s wife, and daughter appearing alive as well as a photo of the body of Lely Kebaki, an old woman who had taken care of Assad’s family when he was a boy as they had to flee Iraq and Saddam.

Assad’s life before Department Q is quite revealing and he will be supported by Morck and company, Roe and Gordon, including the new Chief of Homicide, Marcus Jacobsen.  Adler-Olsen provides a tense novel with a number of twists and turns linking the past and the present.  Morck’s quick wit and sarcasm is on full display as is the commentary provided by his assistant Rose, a depressive personality who has returned to Department Q after an absence of two years.

Adler-Olsen may have been a juggler in a previous life because he is able to maintain a number of plots floating in the air, all at the same time.  VICTIM 2117 is a complex story that as you read on it is very difficult to put down as Assad tries to locate his arch enemy and rescue his family who he is afraid he will not recognize and conversely will not recognize him.  As the novel is about to come to fruition and you think the terror will subside, Adler-Olsen introduces another twist that will leave you hanging.  If the book is as satisfying as I believe you will probably want to consult Adler-Olsen’s previous seven books dealing with the adventures of Department Q.

APEIROGON: A NOVEL by Colum McCann

(Israeli settlers waving the flag at Palestinian demonstrators by the “separation wall”)

The Palestinian-Israeli conflict has transpired for at least a century if one accepts the Balfour Declaration as its origin in 1917 and it developed into an ongoing struggle for its participants in 1948 with the creation of the state of Israel.  After numerous wars, intifadas, and a daily application of violence the toll on all people has been horrendous.  With that as a background Colum McCann introduces his latest novel, APEIROGON an attempt to provide insight into suffering and the intangibles that allow this conflict to persist to this day.  According to the dictionary an apeirogon is “a polygon having an infinite number of sides and vertices” which fits the structure of McCann’s work.  The author describes his new book as “a hybrid novel with invention at its core, a work of storytelling, weaves together elements of speculation, memory, fact, and imagination” the core of which is the relationship between Rami Elhanan, a sixty-seven year old Israeli whose daughter, Smadar was killed in a 1997 suicide bombing in Jerusalem, and Bassam Aramin, a forty-eight year old Palestinian whose daughter, Abir was killed by an Israeli rubber bullet on the West Bank in 2007.  McCann’s inspiration to write the novel is the real-life friendship between Rami and Bassam, two men united in their grief and their life’s work was to tell the story of what happened to their daughters.  The book is labeled a novel but in reality, it is a combination of fiction and non-fiction whose events are recognizable to those who follow the region, though even what appears to be fiction can be categorized as real.

McCann employs birds as a symbolic means of describing the plight of the Palestinian and to a lesser extent the Israeli people.  The migratory birds who travel freely know no boundaries which is in sharp contrast to the limitation of movement for the Palestinian people who must navigate “the Wall” constructed by the Israeli government to separate the West Bank and Israel, the numerous military checkpoints that are employed by the Israeli government, and the Israeli policy of apartheid.

The retelling of Rami and Bassam’s life histories is poignant.  Rami fought in the 1973 Yom Kippur War is married with four children living in Jerusalem with a career as a graphic artist.  Bassam was a militant in his youth and at seventeen was imprisoned, beaten and tortured.  He would remain incarcerated for seven years and upon his release his life took a different turn as he pursued poetry, married and became the father of five children.  His family lived in the village of Anata which is located next to the Shu’fat refugee camp.

Israel is a society under constant surveillance either by the Mossad, military patrol, satellites, and blimps.  McCann effectively describes Rami’s dilemma as a person who has seen too much violence and believes that peace can only come through honest negotiations and compromise.  He “often felt that there were nine or ten Israelis inside him, fighting.  The conflicted one. The shamed one.  The enamored one.  The bereaved one.  The one who marveled at the blimp’s invention.  The one who knew the blimp was watching.  The one watching back.  The one who wanted to be watched.  The anarchist.  The protestor.  The one sick and tired of all the seeing.”  Bassam would go on to co-found Combatants for Peace which is used by McCann to delve into Israeli-Palestinian frustrations and hatred for the status quo as he explores the daily indignities that the Palestinian people experience.

Map of West Bank

McCann defines the effect of the Nakba on the Palestinian people, and the effect of the Holocaust on Israelis.  He compares the two and how they have similar meanings to their individual victims.  McCann integrates the history of the Holocaust and the Palestinian-Israeli conflict throughout.  The removal of Palestinians from their homes during the 1948 war, life in refugee camps along with a very disturbing description of Theresienstadt, and Smadar’s grandfather’s inability to discuss surviving the concentration camps for many decades comes to the fore.  Bassam will travel to England to enroll in Bradford University to earn an advanced degree in Holocaust studies.  He wanted to talk and learn about the use of the past as a means of justifying the present.  “About the helix of history, one moment bound to the next.  About where the past intersected with the future.”  For Bassam he needed clarity for the past, present, and the future.

Rami and Bassam met at a hotel picnic table where eight Israelis and three Palestinians were gathering for the Combatants for Peace.  Rami had founded his own organization Parents Circle and was curious when his son Elik had invited him to attend.  To be a member of the Circle one had to have lost a child, to be one of the bereaved.  This was the beginning of an important personal relationship as Rami and Bassam would learn to lean on each other in crisis’.

Numerous historical figures appear throughout McCann’s rendition of the Palestinian-Israeli crisis.  Biblical figures abound, Roman history is recounted, the 19th century explorer-philosopher, Sir Richard Burton, Albert Einstein, Sigmund Freud, Mohammad Ali, John Kerry, Yasir Arafat, Pablo Picasso, Philippe Petit, General Matti Peled, Smadar’s grandfather and peace advocate, and George Mitchell, the last person who was tasked to bring peace to the region.  McCann accurately describes the “smashed jigsaw” that Mitchell confronted that included PLO, JDL, LEHI, PFLP, ALA, PIJ, CPT, IWPS, ICAHD, AIC, AATW, EIJ, JTJ, ISM, AEI, NIF, ACRI, RHR, BDS, PACBI, BNC and the difficulty of deciding where to begin.

To compare the raw emotions that Rami and Bassam have dealt with is heart rendering.  But also, the realization by Rami that it is “a disaster to discover the humanity of your enemy, his nobility, because then he is not your enemy anymore, he just can’t be.”  As each has to deal with the Israeli bureaucracy and military as it tries to learn the plight of their daughters on the day they were murdered is heart wrenching.  It is symbolic of the time period in which we live.  Novels dealing with this topic are at times a product of events. In the 1990s with the Oslo Accords, novelists could be more upbeat, but today as each side has retreated into belligerent isolation with Donald Trump making a farce of the peace process it is not surprising what McCann delivers in his novel.  But the lesson that emerges is that “the only revenge is making peace.”

As Julie Orringer writes in her New York Times, February 24, 2020 review, “Apeirogon is an empathy engine, utterly collapsing the gulf between teller and listener.  By replicating the messy nonlinear passage of time, by dealing in unexpected juxtapositions that reveal latent truths, it allows us to inhabit the interiority of human beings who are not ourselves.  It achieves its aim by merging acts of imagination and extrapolation with historical fact.  But it’s indisputably a novel, and to my mind, an exceedingly important one.  It does far more than make an argument for peace; it is, itself, an agent of change.”

“I began to think, Rami tells us in his central chapter, that I had stumbled upon the most important question of them all:  What can you do personally, in order to try and help prevent this unbearable pain for others?

McCann has registered his answer, one so powerful that it impels us to find our own.”

The Separation Wall and the Sh'uafat Refugee Camp are seen following a snow storm, on February 20, 2015. Yotam Ronen / Activestills.org

(Separation wall between Israel and the West Bank)

NEPTUNE: THE ALLIED INVASION OF EUROPE AND THE D DAY LANDINGS by Craig L. Symonds

image__header__normandy-visit-the-omaha-beach-american-cemetery-memorial-in-colleville-sur-mer__croix-r-ale-goff-calvadostourismejpg

(American Cemetery at Normandy)

Last year there were a number of new books that appeared commemorating the 75th anniversary of the D Day landing in June 1944.  These books include COUNTDOWN TO D DAY: THE GERMAN PERSPECTIVE by Peter Margaratis, NORMANDY ’44: D DAY AND THE EPIC 77 DAY BATTLE FOR FRANCE by James Holland, SAND AND STEEL: D DAY AND THE LIBERATION OF FRANCE by Peter Caddick-Adams, THE FIRST WAVE:THE D DAY WARRIORS WHO LED THE WAY TO VICTORY IN WORLD WAR II by Alex Kershaw, and SOLDIER, SAILOR, FROGMAN, SPY, AIRMAN, GANGSTER, KILL OR DIE: HOW THE ALLIES WON ON D DAY by Giles Milton.  Another important book appeared in 2014, Craig L. Symonds, NEPTUNE: THE ALLIED INVASION OF EUROPE AND THE D DAY LANDINGS.

Symonds the author of THE BATTLE OF MIDWAY, and LINCOLN AND HIS ADMIRALS does a remarkable job describing the preparation and implementation of allied plans for a cross channel invasion that culminated on June 6, 1944 in NEPTUNE: THE ALLIED INVASION OF EUROPE AND THE D DAY LANDINGS.  The book is broken down into two parts. First, Symonds explores the coming together of the British-American special relationship that begins following the Nazi invasion of Poland in September 1939, the role of Franklin D. Roosevelt and Winston Churchill, and the integration of allied planning for the invasion with the personalities of Dwight Eisenhower, George C. Marshall, Sir Alan Brooke, General Bernard Montgomery and a host of others.  The second half of the narrative delves into the placement of allied shipping and personnel in England and their preparation for the invasion, and the actual landings themselves culminating in the allied attempt to drive the Germans out of Cherbourg.  The book is heavily researched including interviews with survivors, archival material, and the leading secondary works.

Symonds takes the reader through all the major conferences and planning sessions that took place between 1941 (nine months before Pearl Harbor) and 1944 and breaks down the major issues from unity of command, the disagreement over which should take precedence a cross channel invasion or landing in the Mediterranean theater, the number of troops and shipping needed, what types of landing craft should be employed, and the actual timing of any invasion.  According to Symonds the key to D Day was Operation TORCH, the allied invasion of North Africa.  All the major issues that would emerge for a cross channel invasion were already present in preparing TORCH which would become a dress rehearsal for D Day – creating a multi-national force under one allied commander.  In the end TORCH was a success but it highlighted that a great deal of work needed to be done to prepare for Operation OVERLORD.

What makes Symonds narrative so compelling are the numerous insights he offers.  Especially interesting is his analysis of the cultural differences between British and American society that led to the low opinion that the British had of American soldiers, the American approach to war, and the attitude they felt Americans engendered. The British believed that they had been fighting for a number of years while the Americans may have produced their weaponry, shipping, and other necessities they did not have the combat experience and know how of British planners and soldiers.  On the other hand, Americans viewed the British as rather haughty, slow in preparation, and in part beholden to the United States.  Symonds explanation of the pros and cons of the Anglo-American relationship is very valuable and reflects how they were dependent upon each other.

File:General George C. Marshall, official military photo, 1946.JPEG

(General George C. Marshall)

What separates Symonds account from others is his focus on the different types of landing craft that were needed for OVERLORD, how each fit a particular need, the necessary ingenuity particularly on the part of the British, and the production process and schedules that were developed.  Symonds breaks down each type of landing craft and points out the differences of each, the training components, their positive aspects and design flaws, and overall, how important they were to the success of D Day.

Symonds explores the experiences of the soldiers who were dependent upon the landing craft as they departed the 171 launching sites dispersed around England, Scotland, and Northern Ireland, their experiences in the channel, and what it was like to land on the Normandy beaches.  Symonds delves into production issues that forced a one-month postponement of OVERLORD in addition to the weather issues that would force a postponement of one day to launch the operation and forced Eisenhower to smoke even more cigarettes than normal!

Symonds is correct when he points out that despite the massive allied firepower the overall impact, particularly on Omaha Beach turned out to be less than hoped for.  “….the bombs fell too long, the rockets fell to short, and the naval gunfire was too brief.  Ashore, the Germans crouched down in their bomb proof shelters, many with concrete walls five feet thick, and they covered their ears, but none of the Allied ordnance penetrated their bunkers and pill boxes.”

Symonds is dead on in arguing that OVERLORD contained so many working parts with a timetable that made each element dependent on so many others.  As a result, early errors created a series of difficulties that threatened to ruin the invasion especially on Omaha Beach.  However, in the end what saved the day “was the ability of the men both afloat and ashore to adapt and adjust.”  Further, what saved the day for those dealing with the heavy German guns were the destroyers in the channel that maneuvered expertly and were able to rein hellfire on the well ensconced German pill boxes.  It was clear that even though Omaha Beach fell into allied hands the assault had not gone according to plan and Symonds describes the reasons for the failure.  It would take over 10,000 casualties, 3,000 of which occurred on Omaha Beach, a sum greater than the losses on all four of the other invasion beaches combined.

 

Symonds integrates the personal stories of the men who fought and died on D Day into the narrative.  Whether describing the men who climbed Pointe du Hoc to knock out heavy German artillery; the men who climbed the bluffs to the shock of the German gunners; Ensigns who found themselves in command of landing craft; or those who splashed in the water or crawled onto the beaches under withering German fire Symonds tells their stories in a clear fashion so one can get a feel for what these brave individuals experienced.

The book reads like a work of fiction in parts particularly as the author discusses the planning stage.  It morphs into more of a non-fictional work as he gets into the nitty gritty of the types of ships that were employed.  If there is a criticism to be made it is that Symonds approach seems a bit American-centered.   However, in the end this is an efficient work that is well written and should maintain reader interest.  I look forward to reading Symonds latest work WORLD WAR II AT SEA: A GLOBAL HISTORY soon.

File:CambridgeAmericanCemetery.jpg

(American Cemetery at Normandy)

BOTTLE OF LIES: THE INSIDE STORY OF THE GENERIC DRUG BOOM by Katherine Eban

 

Ranbaxy building
(Ranbaxy plant in Mohali, India)

The other day I was chatting with my doctor and I mentioned to him that he should consider reading Katherine Eban’s recent book, BOTTLE OF LIES: THE INSIDE STORY OF THE GENERIC DRUG BOOM.  He was not familiar with the title but as we chatted about the role of India and China in reverse engineering American brand name medications his eyes lit up.  My physician is of Indian descent and he described to me what he witnessed when visiting India and the practices pursued by Indian generic drug manufacturers, particularly Ranbaxy.  He described disingenuous practices, fraud, corruption, the lack of government oversight and a myriad of illegal practices pursued by companies that went against the FDA’s best practices protocols.  Since 40% of all generic drugs are produced in India and 80% of the active ingredients in all drugs are produced in India and China his comments were eye opening and affirmed what Eban lays out in her investigative narrative of the generic drug industry and raised in my mind whether the new medication I was about to ingest was based on correct data and honest productive practices.  According to Eban, Americans should think twice when taking medications which puts people in a quandary – you need the medication, but can they be trusted?

The narrative that Eban has produced can best be described as “mind blowing.”  As one Dutch pharmaceutical executive described the generic industry as being similar to the meatpacking productive processes described by Upton Sinclair in his book, THE JUNGLE at the turn of the 20th century.  Eban delineates the gulf that exists between what regulations require of generic drug companies and how those companies operated.  Their goal is to minimize costs and maximize profits.  To achieve this companies circumvented regulations and resorted to fraud: “manipulating tests to achieve positive results and concealing or altering data to cover their tracks.  By making the drugs cheaply without regard to safeguards and then selling them into regulated and more costly Western markets, claiming that they had followed all necessary regulations, companies could reap enormous profits.”

FDA Building

The key figure in the first half of the narrative was Dinesh S. Thakur, who was employed by Bristol-Myers, Squibb in Hopewell, NJ where he ran a department that built robots and other automated products designed to make drug testing more efficient and reliable.  Thakur’s problems began when he decided to leave his position in the United States and took one at Ranbaxy Laboratories located in India.  Almost immediately Thakur witnessed extensive fraud and a lack of transparency at the company.  Within two years Thakur’s friend, Rashmi Barbhaiya who convinced him to accept a position at Ranbaxy left the company leaving Thakur to fend for himself.  The first issue was HIV medications for South Africa which had a number of defects and the company refused to recall them.  As time went on Thakur would soon learn that Ranbaxy faked over 50% of its dossiers to the Food and Drug Administration (FDA); 100% for India; and 50% for Europe.  Thakur ordered a breakdown of every product, year by year of each dossier.  Ranbaxy used data as a fungible marketing tool without consideration for the impact its drugs had on patients.  “The company manipulated almost every aspect of the manufacturing process to quickly produce impressive looking data that would bolster its bottom line.”  Ranbaxy’s approach was to do whatever it could get away with the patients be damned.

Eban unravels the crimes and conspiracies involved in Ranbaxy’s approach to developing and producing generic drugs, layer by layer.  The company had no written protocols for investigating physician and patient complaints and viewed FDA regulations as an obstacle to be gamed.  When Dr. Kathy Spreen, Ranbaxy’s American Executive Director of Clinical Medicine uncovered the fraud dealing with Aids drugs she expressed her concerns to a company executive who responded, “Who Cares…It’s only blacks dying.”  When another friend of Thakur, Rajinder Kumar resigned because of company practices, Thakur was targeted by executives because of his complaints and when executives threatened him and his family, he also left the company. Eban’s focus on Thakur’s experiences reads like a crime novel.  He smuggled out damning evidence against the company and became a whistleblower for the FDA.  His life was a mess and his experience were chilling as he feared he would be outed, and his family would pay the price.

dinesh-thakur

(Dinesh S. Thakur)

The theme that dominates Eban’s narrative is that Ranbaxy’s approach to its manufacturing process, covering up its misbehavior, its dealings with the FDA, and the callousness of its executives was a recurring problem throughout the generic drug industry for decades.  A number of cases highlight this process.  First, executives would smuggle out brand named drugs from the United States in their luggage to be reverse engineered in India and then made up data to apply for the first time right of a generic to the FDA – executives became “drug mules!”  Second, plant inspections in India by the FDA were a game of cat and mouse.  There were no surprise visits by FDA personnel as part of the process, so Indian companies had weeks to prepare for visits, falsifying data, shredding negative data, and putting on a dog and pony show for investigators.  Eban describes numerous examples of this process at a series of Ranbaxy plants in India.  Third, and possibly the most egregious was the sale of a controlling interest in Ranbaxy to a Japanese company, Daiichi Sankyo.  The sale would provide $2 billion for Malvinder Singh, the company CEO and his brother.  However, as soon as the deal was completed Daiichi Sankyo learned that Ranbaxy was in trouble with the US Justice Department and the FDA as their products would no longer be approved for sale in the US until they could prove their products were not fraudulent.  Fourth, the sale of tainted heparin used for dialysis in the United States killing 31 Americans.  What emerged is that chemists were bribed, further data was falsified, the Ranbaxy pattern continued.  The last example, among many is Eban’s dive into FDA dealings with Ranbaxy over its attempt to gain approval of its version of Lipitor, atorvastatin.  Ranbaxy faked atorvastatin records before FDA investigators visited Paonta Sahib, the manufacturing site.  Eban presents company emails and FDA documentation proving that Ranbaxy was not to be trusted and in the end because of pressure by Congress which needed the lower price as the drug was considered an integral part of the new Affordable Care Act they gamed the system once again and gained approval.

Thakur is not the only one to experience the deceit of the Indian generic industry.  Eban describes how Dr. Harry Lever, a Cleveland Clinic cardiologist discovered that when his patients switched from brand name drugs to generics their health greatly deteriorated.  Dr. Randall Starling, a member of the Cleveland Clinic Heart Failure and Cardiac Transplant Medicine team uncovered that the generic version of tacrolimus, made by Dr. Reddy’s Laboratories, an Indian company caused major issues with his transplant patients.  Eban’s discussion of Joe and Jerry Graedon who for over thirty years had a syndicated newspaper column and a patient advocate NPR program realized through their own research that FDA standards in approving generic medication were extremely flawed and eye opening.  All of these examples lead one to believe that the generic industry produces one horror show after another and the under funded and understaffed FDA with little access to the truth in India can not protect American patients, or for that matter foreign markets that Indian companies supply with medications.

Aside from Thakur there are a number of important personages in Eban’s expose and the one that stands out the most is Peter Baker.  In 2008 Baker joined the FDA and soon became its most important foreign investigator.  A no nonsense individual who thought nothing of jumping into a dumpster to find evidence of fraud and god knows what else as he became the bane of Ranbaxy and other companies’ existence.  His work in India and China, the threats he dealt with from foreign companies, and even opposition within the FDA who at times saw him as a “cowboy” probably resulted in saving countless lives.  Baker’s discoveries boggle the mind and provide unbelievable insights into the minds of foreign generic executives and their approach to the manufacturing process and the frauds they engaged in.

The further one reads Eban’s expose the more distressing the information becomes.  It seemed it was standard practice for the generic companies to make different versions of the same product, high quality drugs for the Western markets, and low-quality ones for lower income countries which was highlighted by Eban’s reportage of the drug Lipitor.  Eban’s work is very important and I found myself checking the labels on my own medication and where they were manufactured as I became immersed in the book producing a great deal of anxiety on my part.  It seems that what started in Mahatma Gandhi’s ashram as a campaign of Indian self-reliance had morphed into a pharmaceutical rescue mission for the world’s most unfortunate patients. It is obvious that Eban’s work is extremely one sided which can be seen as a criticism, but in reality, how could it be anything different based on her findings especially since her research is impeccable.  The book should have a label for patients on the cover because it will create extreme angst in anyone who reads it.

Statins: Different strengths of Atorvastatin, trade name Lipitor, made by Pfizer Stock Photo